The friendship match attracted a large number of football fans and around 200 international reporters.
Returning from a long training session in Europe, Palestinian players, who were physically on good form, dominated the game on their home turf.
Vietnamese players fought hard to repel Palestine attacks, but failed to keep their clean sheet. They made mistakes and let their rivals score two goals in the 20th and 77th minutes of the game.
The game was witnessed by senior Palestine leaders, including president Mahmoud Abbas.
On May 16, the U19 Vietnam team will meet Pakistan.
The tournament has drawn the participation of 10 teams, namely Palestine, Sri Lanka, Uzbekistan, Indonesia, Iraq, Tunisia, Jordan, Mauritania, Pakistan, and Vietnam.
Vietnam is competing against Palestine, Pakistan and Sri Lanka in Group A.